> At a Glance
> – Oprah Winfrey says GLP-1 medication stopped her tequila habit.
> – She reports feeling more alive, vibrant, and energetic.
> – The drug also lifted her shame about weight loss.
> – Why it matters: It shows GLP-1s can transform health habits beyond weight control.
Oprah Winfrey revealed that a weight-loss drug, GLP-1, has changed more than just her body. The 71-year-old says it eliminated her urge to drink alcohol and boosted her overall vitality.
Alcohol Habits Transform
During a December 30 interview, Winfrey admitted she once enjoyed tequila, even taking 17 shots in one night. She now says she no longer feels the desire to drink.
Oprah Winfrey stated:
> “I was a big fan of tequila. I literally had 17 shots one night.”
Oprah Winfrey added:
> “The fact that I no longer even have a desire for it, is pretty amazing.”
- She cites GLP-1s as the reason for her newfound abstinence.
- The change is part of a broader health overhaul.
- She encourages others to consider medical options.
Energy & Weight-Loss Gains
Winfrey says she feels more alive and vibrant than ever. She claims she no longer punishes herself and has more energy for loved ones.
Oprah Winfrey noted:
> “I feel more alive and more vibrant than I’ve ever been. I’m not constantly punishing myself. I hardly recognize the woman I’ve become. But she’s a happy woman.”
- She credits GLP-1s for sustained weight loss.
- She attributes increased energy to reduced cravings.
- She feels more open and generous toward others.
Mindset Shift on Obesity
The media mogul also discussed her changing view on obesity. She avoids the word “obesity” because it implies loss of control.
Oprah Winfrey reflected:
> “I avoided the word ‘obesity.’ It connoted ‘out of control.’ But I came to understand that overeating doesn’t cause obesity. Obesity causes overeating. And that’s the most mind-blowing, freeing thing I’ve experienced as an adult.”
She urges people to stop blaming genes or environment and to use the information to choose what works for them.
Key Takeaways

- GLP-1 medication stopped Oprah’s alcohol cravings.
- She reports feeling more vibrant, energetic, and less self-punishing.
- Her perspective on obesity shifted to seeing overeating as a consequence, not a cause.
Oprah’s story highlights how a single medication can ripple across lifestyle, mindset, and health.

